CanIsoNet

Gene Name:

Transcript ID:
Transcript Name:
dMDT Interaction Network

Protein interaction losses due to MDT switch
*only proteins having domain-domain interaction information are taken into consideration
Number of Total Interaction:
Number of Lost Interaction:
Gene Name Interaction Lost Lost Domain (Region) Lost Domain - Domain Interaction
GRB14 GRB14-INSR SH2(439-520) SH2(439-520) - fn3
GRB14 GRB14-TEK SH2(439-520) SH2(439-520) - fn3
GRB14 GRB14-PRKCI SH2(439-520) SH2(439-520) - C1_1
GRB14 GRB14-PRKCZ SH2(439-520) SH2(439-520) - C1_1
GRB14 GRB14-FGFR1 SH2(439-520) SH2(439-520) - Pkinase_Tyr

Network Density Score: %

The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch
Sample ID Disease Type Gene Name 1 Gene Name 2 Transcript Name dMDT
78029317-b987-4292-abfe-fe6a1036c805 Pancreas.Panc-AdenoCA GRB14 INSR GRB14-002 ENST00000446413
78029317-b987-4292-abfe-fe6a1036c805 Pancreas.Panc-AdenoCA GRB14 TEK GRB14-002 ENST00000446413
78029317-b987-4292-abfe-fe6a1036c805 Pancreas.Panc-AdenoCA GRB14 PRKCI GRB14-002 ENST00000446413
78029317-b987-4292-abfe-fe6a1036c805 Pancreas.Panc-AdenoCA GRB14 PRKCZ GRB14-002 ENST00000446413
78029317-b987-4292-abfe-fe6a1036c805 Pancreas.Panc-AdenoCA GRB14 FGFR1 GRB14-002 ENST00000446413
Interaction losses with Clinvar proteins
Gene Name
FGFR1
INSR
TEK