dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| ITK | ITK-LCP2 | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-PLCG1 | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-BLK | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-ZAP70 | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-YES1 | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-LCK | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-GRB2 | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-GRAP2 | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-FYN | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-SRC | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-PLCG2 | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-VAV3 | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-VAV2 | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-FGR | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-SYK | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-HCK | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-TEC | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-SH2D2A | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-LYN | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-VAV1 | SH2(239-323) | SH2(239-323) - SH2 |
| ITK | ITK-PIK3CB | SH2(239-323) | SH2(239-323) - PI3_PI4_kinase |
| ITK | ITK-PIK3CG | SH2(239-323) | SH2(239-323) - PI3_PI4_kinase |
| ITK | ITK-PIK3CD | SH2(239-323) | SH2(239-323) - PI3_PI4_kinase |
| ITK | ITK-SOS1 | SH3_1(177-223) | SH3_1(177-223) - PH |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch