dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| PTPN12 | PTPN12-CSK | Y_phosphatase(58-291) | Y_phosphatase(58-291) - SH2 |
| PTPN12 | PTPN12-GRB2 | Y_phosphatase(58-291) | Y_phosphatase(58-291) - SH2 |
| PTPN12 | PTPN12-SRC | Y_phosphatase(58-291) | Y_phosphatase(58-291) - SH2 |
| PTPN12 | PTPN12-JAK2 | Y_phosphatase(58-291) | Y_phosphatase(58-291) - SH2 |
| PTPN12 | PTPN12-SHC1 | Y_phosphatase(58-291) | Y_phosphatase(58-291) - SH2 |
| PTPN12 | PTPN12-FLT3 | Y_phosphatase(58-291) | Y_phosphatase(58-291) - Pkinase_Tyr |
| PTPN12 | PTPN12-EGFR | Y_phosphatase(58-291) | Y_phosphatase(58-291) - Pkinase_Tyr |
| PTPN12 | PTPN12-PTK2B | Y_phosphatase(58-291) | Y_phosphatase(58-291) - Pkinase_Tyr |
| PTPN12 | PTPN12-PTK2 | Y_phosphatase(58-291) | Y_phosphatase(58-291) - Pkinase_Tyr |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch