dMDT Interaction Network
Protein interaction losses due to MDT switch
| Gene Name | Interaction Lost | Lost Domain (Region) | Lost Domain - Domain Interaction |
|---|---|---|---|
| PTPN2 | PTPN2-NCK2 | Y_phosphatase(42-274) | Y_phosphatase(42-274) - SH2 |
| PTPN2 | PTPN2-STAT3 | Y_phosphatase(42-274) | Y_phosphatase(42-274) - SH2 |
| PTPN2 | PTPN2-NCK1 | Y_phosphatase(42-274) | Y_phosphatase(42-274) - SH2 |
| PTPN2 | PTPN2-STAT6 | Y_phosphatase(42-274) | Y_phosphatase(42-274) - SH2 |
| PTPN2 | PTPN2-STAT5A | Y_phosphatase(42-274) | Y_phosphatase(42-274) - SH2 |
| PTPN2 | PTPN2-STAT1 | Y_phosphatase(42-274) | Y_phosphatase(42-274) - SH2 |
| PTPN2 | PTPN2-PDGFRB | Y_phosphatase(42-274) | Y_phosphatase(42-274) - Pkinase_Tyr |
| PTPN2 | PTPN2-EGFR | Y_phosphatase(42-274) | Y_phosphatase(42-274) - Pkinase_Tyr |
| PTPN2 | PTPN2-INSR | Y_phosphatase(42-274) | Y_phosphatase(42-274) - Pkinase_Tyr |
| PTPN2 | PTPN2-JAK1 | Y_phosphatase(42-274) | Y_phosphatase(42-274) - Pkinase_Tyr |
| PTPN2 | None | None | None |
Network Density Score: %
The local network of this protein has more interaction than % of all proteins in the proteome.
Statistics on dMDT
*This transcript has been found as a dMDT in these diseases
Samples showing lost interactions due to MDT switch